关于美国麻省大学医学院诸葛荣华博士学术报告的通知

 

Dr. Zhuge obtained BS degree at Zhejiang University in 1983 and doctoral degree at Iowa State University, USA in 1995. Research in his laboratory is focused on quantitative understanding of the ways Ca2+ signals and ion channel activities are controlled and regulated in smooth muscle. Smooth muscle plays pivotal roles in physiological functions such as maintaining blood pressure and regulating bronchial tone. Defects in this type of cell cause congenital and acquired pathological conditions such as hypertension and asthma.  Intracellular calcium is a primary signal in mediating smooth muscle function and ion channels.  They attempt to elucidate mechanisms on how Ca2+ sparks activate the BK and Cl(Ca) channels, to investigate the structure and function of Cl(Ca) channels, and to determine the roles of Ca2+ spark signaling in asthma and other smooth muscle disorders. His recent paper appeared in Nature Medicine (2012; 18:648-650) was “Activation of BK channels may not be required for bitter tastant-induced bronchodilation”, a joint work with his collaborators in Nanjing.

 

 

2012年11月6日