方维焕

学  历：

         1993.11 - 1996.06：芬兰赫尔辛基大学兽医学院 哲学博士

         1982.02 - 1985.01：浙江农业大学兽医系 硕士

         1978.03 - 1982.01：浙江农业大学兽医系 学士

工作简历：

1996.12 - 至今：浙江大学动物科学学院 教授

2006.09 - 2006.12：美国哈佛大学医学院微生物与分子遗传系 访问学者

2001.07 - 2001.10：丹麦皇家兽医与农业大学 访问学者

1996.12 - 1998.12：美国田纳西大学动物科学系 博士后

1992.10 - 1996.11：浙江农业大学动物科学学院 副教授

1988.04 - 1992.09：浙江农业大学兽医系 讲师

1985.02 - 1988.03：浙江农业大学兽医系 助教

2011 - 至今：International Committee on Food Microbiology & Hygiene执行委会会委员(Exe. Board Member)

2008 - 至今：中国畜牧兽医学会常务理事

2013 - 至今：浙江省畜牧兽医学会 理事长

2007 - 至今：Foodborne Pathogens and Disease 编委

2005 - 至今：中国畜牧兽医学会兽医食品卫生学分会 副理事长

2005 - 至今：《微生物学报》编委

2005 - 至今：《中国兽医科学》编委

2004 - 2014：浙江省动物预防医学重点实验室 主任

2002 - 至今：International Journal of Food Microbiology 编委

2000 - 至今：浙江大学动物预防医学研究所 所长

1999 - 至今：《畜牧兽医学报》编委

2008 - 2011：International Journal of Food Microbiology 编辑

1999 - 2009：浙江大学动物科学学院 副院长

    1. 动物疫病和食源性病原感染生物学与控制

    2. 微生物性食品安全

1. Jiang XY, Yang YK, Zhou JJ, Zhu LX, Gu YX, Zhang XY, Li XL, Fang WH. Roles of the Putative Type IV-like Secretion System Key Component VirD4 and PrsA in Pathogenesis of Streptococcus suis Type 2. Frontiers in Cellular & Infection Microbiology, 2016, 6:172.
2. Xue YY, Shi MT, Tu F, Wu CQ, Ren GP, Wang XJ, Fang WH, Song HH, Yang MH. Redox pathway sensing bile salts activates virulence gene expression in Vibrio cholerae. Molecular Microbiology, 2016, 102(5):909-924.
3. Liao X, Wang ZH, Cao T, Tong C, Geng SC, Gu YX, Zhou YS, Li XL, Fang WH. Hypervariable antigenic region 1 of classical swine fever virus E2 protein impacts antibody neutralization. Vaccine, 2016, 34(33):3723-3730.
4. Liang Q, Li WF, Guo NN, Tong C, Zhou YS, Fang WH, Li XL. Identification and functional analysis of interleukin-1β in the Chinese soft-shelled turtle Pelodiscus sinensis. Genes, 2016, 7(5):18.
5. Gu YX, Qi BZ, Zhou YS, Jiang XW, Zhang X, Li XL, Fang WH. Porcine Circovirus Type 2 Activates CaMMKβ to Initiate Autophagy in PK-15 Cells by Increasing Cytosolic Calcium. Viruses, 2016, 8(5):135
6. Zhou YS, Gu YX, Qi BZ, Zhang YK, Li XL, Fang WH. Porcine circovirus type 2b capsid protein induces unfolded protein response with subsequent activation of apoptosis. Journal of Zhejiang University - Science B, 2016, in press.
7. Jiang XW, Yang YK, Zhu LX, Gu YX, Shen HX, Shan Y, Li XL, Wu JS, Fang WH. Live Streptococcus suis type 5 strain XS045 provides cross-protection against infection by strains of types 2 and 9. Vaccine, 2016, 34(51):6529–6538.
8. Wang XD, Shao CY, Wang LY, Li QJ, Song HH, Fang WH. The viral non-structural protein 1 alpha (Nsp1α) inhibits p53 apoptosis activity by increasing murine double minute 2 (mdm2) expression in porcine reproductive and respiratory syndrome virus (PRRSV) early-infected cells. Veterinary Microbiology, 2016, 184:73-79.
9. Shan Y, Zhang YK, Zhuo XH, Li XL, Peng JR, Fang WH. Matrix metalloproteinase-9 plays a role in protecting zebrafish from lethal infection with Listeria monocytogenes by enhancing macrophage migration. Fish & Shellfish Immunology, 2016, 54, 179-187.
10. Zhou YS, Qi BZ, Gu YX, Xu F, Du HH, Li XL, Fang WH. Porcine circovirus 2 deploys PERK pathway and GRP78 for its enhanced replication in PK-15 cells. Viruses, 2016, 8(2):56.
11. Xia Y, Xin YP, Li XL, Fang WH. To modulate survival under secondary stress conditions, Listeria monocytogenes 10403S employs RsbX to down-regulate σB activity in the post-stress recovery stage or stationary phase. Applied & Environmental Microbiology, 2016, 82(4):1126-1135.
12. Fang C, Cao T, Shan Y, Xia Y, Xin YP, Cheng CY, Song HH, Bowman J, Li XL, Zhou X, Fang WH. Comparative genomic analysis teveals that the 20K and 38K prophages in Listeria monocytogenes serovar 4a strains Lm850658 and M7 contribute to genetic diversity but not to virulence. Journal of Microbiology & Biotechnology, 2016, 26(1):197-206.
13. Fang C, Shan Y, Cao T, Xia Y, Xin YP, Cheng CY, Song HH, Li XL, Fang WH. Prevalence and virulence characterization of Listeria monocytogenes in chilled pork in Zhejiang province, China. Foodborne Pathogens and Disease, 2016, 13(1):8-12.
14. Cheng CY, Wang XD, Dong Z, Shao CY, Yang Y, Fang WH, Fang CC, Wang H, Yang MH, Jiang LL, Zhou X, Song HH. Aminopeptidase T of M29 Family Acts as A Novel intracellular virulence factor for Listeria monocytogenes infection. Scientific Report. 2015, 5:17370.
15. Zhang X, Wang X, Sun MJ, Zhang X, Song HH, Yan Y, Sun J, Li XL, Fang WH. A magnetic nanoparticle-based enzyme-linked immunosorbent assay for sensitive quantification of zearalenone in cereal and feed samples. Toxins (Basel), 2015, 7(10):4216-31.
16. Zhang X, Sun MJ, Kang Y, Xie H, Wang X, Song HH, Li XL, Fang WH. Identification of a high-affinity monoclonal antibody against ochratoxin A and its application inenzyme-linked immunosorbent assay. Toxicon, 2015,106:89-96.
17. Wang L, Wang R, Kong BW, Jin S, Ye K, Fang WH, Li YB. B cells using calcium signaling for specific and rapid detection of Escherichia coli O157:H7. Scientific Report, 2015, 5:10598.
18. Shan Y, Fang C, Cheng CY, Wang Y, Peng JR, Fang WH. Immersion infection of germ-free zebrafish with Listeria monocytogenes induces transient expression of innate immune responses. Frontiers in Microbiology, 2015, 6:373.
19. Fang C, CaoT, Cheng CY, Xia, Y, Shang Y, Xin YP, Guo NN, Li XL, Song HH, Fang WH. Activation of PrfA results in overexpression of virulent factors but does not rescue the pathogenicity of Listeria monocytogenes M7. Journal of Medical Microbiology, 2015, 64(8):818-827.
20. Zhang XF, Li K, Wu S, Shuai JB, Fang WH. Peptide nucleic acid fluorescence in-situ hybridization for identification of Vibrio spp. In aquatic products and environments. International Journal of Food Microbiology, 2015, 206:39-44.
21. Fang LH, Shen HX, TangYL, Fang WH. Superoxide dismutase of Streptococcus suis serotype 2 plays a role in anti-autophagic response by scavenging reactive oxygen species in infected macrophages. Veterinary Microbiology, 2015, 176(3-4)328-336.
22. Hu QL, Wu M; Fang C, Cheng CY, Zhao MM, Fang WH, Chu P, Ping Y，Tang GP. Engineering Nanoparticle-Coated Bacteria as Oral DNA Vaccines for Cancer Immunotherapy. Nano Letters, 2015, 15 (4):2732–2739.
23. Zhang XY, Jiang XW, Yang L, Shen HX, Lu XM, Fang WH. DnaJ of Streptococcus suis type 2 contributes to cell adhesion and thermotolerance. Journal of Microbiology and Biotechnology, 2015, 25(6):771-781.
24. Yu Y, Fang LH, Zhang Y, Shen HX, Fang WH. VgrG2 of typeVI secretion system 2 of Vibrio parahaemolyticus induces autophagy in macrophages. Frontiers in Microbiology, 2015, 6:168.
25. Cheng CY, Yang YC, Dong ZM, Wang XW, Fang C, Yang MH, Sun J, Xiao LY, Fang WH, Song HH. Listeria monocytogenes varies among strains to maintain intracellular pH homeostasis under stresses by different acids as analyzed by a high-throughput microplate-based fluorometry. Frontiers in Microbiology, 2015, 6:15.
26. Tong C, Chen N, Liao X, Xie WQ, Li DJ, Li XL, Fang WH. The Epitope Recognized by Monoclonal Antibody 2B6 in the B/C Domains of Classical Swine Fever Virus Glycoprotein E2 Affects Viral Binding to Hyperimmune Sera and Replication. Journal of Microbiology and Biotechnology, 2015, 25(4):537-546.
27. Hu HX, Zhang X, Zhang HS, Wen GL, Zhang QQ, Li XL, Fang WH. Porcine reproductive and respiratory syndrome virus inhibition of interferon-β transcription by IRF3-independent mechanisms in MARC-145 cells in early infection. Veterinary Immunology and Immunopathology, 2013, 156:135-140.
28. Wang W, Li M, Fang WH, Li YB. A predictive model for assessment of decontamination effects of lactic acid and chitosan used in combination on Vibrio parahaemolyticus in shrimps. International Journal of Food Microbiology, 2013, 167(2):124-30.
29. Chen, J., C. Cheng, Y. Lv & Fang WH. Genetic diversity of internalin genes in the ascB -dapE locus among Listeria monocytogenes lineages III and IV strains. Journal of Basic Microbiology, 2013, 53(9):778-84.
30. Li M, Wang W, Fang WH, Li YB. Inhibitory effects of chitosan coating combined with organic acids on listeria monocytogenes in refrigerated ready-to-eat shrimps. Journal of Food Protection, 2013, 76:1377–1383.
31. Shuai JB, Zhang XF, Chen WJ, Li K, Wu S, He YQ, Fang WH. In vivo characterization of chimeric PCV DNA clones containing heterogeneous capsid protein nuclear localization signals (NLS). Virology Journal 2013, 10:16.
32. Wen GL, Zhang Y, Zhang X, Hua HX, Cheng CY, Wang XD, Li XL, Fang WH. Functional characterization of porcine LSm14A in IFN-induction. Veterinary Immunology and Immunopathology, 2013, 155:110-116.
33. Cheng CY, Chen JS, Fang C, Xia Y, Shan Y, Liu Y, Wen GL, Song HH, Fang WH. Listeria monocytogenes aguA1, but not aguA2, encodes a functional agmatine deiminase: Biochemical characterization of its catalytic properties and roles in acid tolerance. Journal of Biological Chemistry, 2013, 288:26606-26615.
34. Cheng CY, Chen JS, Shan Y, Fang C, Liu Y, Xia Y, Song HH, Fang WH. Listeria monocytogenes ArcA contributes to acid tolerance. Journal of Medical Microbiology, 2013, 62:813-821.
35. Zhu BL, Zhou YS, Xu F, Shuai JB, Li XL, Fang WH. Porcine Circovirus Type 2 Induces Autophagy via AMPK/ERK/TSC2/mTOR Signaling Pathway in PK-15 Cells. Journal of Virology, 2012, 86(22): 12003-12012.
36. Tang YL, Wu W, Zhang XY, Lu ZY, Chen JS, Fang WH. Catabolite control protein A of Streptococcus suis type 2 contributes to sugar metabolism and virulence. The Journal of Microbiology, 2012, 50(6):994-1002.
37. Yu Y, Yang H, Li J, Zhang PP, Wu BB, Zhu BL, Zhang Y, Fang WH. Putative type VI secretion systems of Vibrio parahaemolyticus contribute to adhesion to cultured cell monolayers. Archives of Microbiology, 2012, 194(10):827-835.
38. Tang YL, Zhang XY, Wu W, Lu ZY, Fang WH. Inactivation of the sodA gene of Streptococcus suis type 2 encoding superoxide dismutase leads to reduced virulence to mice. Veterinary Microbiology, 2012, 158(3-4):360-366.
39. Zhang XF, Wu S, Li K, Shuan JB, Dong Q, Fang WH. Peptide nucleic acid fluorescence in situ hybridization for identification of Listeria genus, Listeria monocytogenes and Listeria ivanovii. International Journal of Food Microbiology, 2012, 157:309–313
40. Chen JS, Fang C, Zhu NY, Lv YH, Cheng CY, Bei YJ, Zheng TL, Fang WH. Genetic organization of ascB-dapE internalin cluster serves as a potential marker for Listeria monocytogenes sublineages IIA, IIB and IIC. Journal of Microbiology and Biotechnology, 2012, 22(5):575-584.
41. Li XL, Kang Y, Zhang XY, Zhu BL, Fang WH. Identification of a heat-shock cognate 70 gene in Chinese soft-shell turtle (Pelodiscus sinensis) and its expression profiles under thermal stress. Journal of Zhejiang University SCIENCE B (Biomedicine & Biotechnology). 2012, 13(6):465-477.
42. Zhu BL, Xu F, Li L, Shuai JB, Li XL, Fang WH. Porcine circovirus type 2 explores the autophagic machinery for replication in PK-15 cells. Virus Research, 2012, 163:476-485.
43. Chen JS, Fang C, Zheng TL, Zhu YY, Bei YJ, Fang WH. Genomic presence of GadD1 glutamate decarboxylase correlates with the organization of ascB-dapE internalin cluster in Listeria monocytogenes. Foodborne Pathogens and Disease, 2012, 9:175-178.
44. Tang YL, Zhao HC, Wu W, Wu D, Li XL, Fang WH. Genetic and virulence characterization of Streptococcus suis type 2 isolated from swine in Provinces of Zhejiang and Henan, China. Folia Microbiology, 2011, 56:541-548.
45. Chen JS, Cheng CY, Xia Y, Zhao HX, Fang C, Shan Y, Wu BB, Fang WH. Lmo0036, an ornithine and putrescine carbamoyltransferase in Listeria monocytogenes, participates in arginine deiminase and agmatine deiminase pathways and mediates acid tolerance. Microbiology, 2011, 157:3150-3161.
46. Yu Y, Hu WZ, Wu BB, Zhang PP, Chen JS, Wang SN, Fang WH. Vibrio parahaemolyticus isolates from southeastern Chinese coast were genetically diverse with circulation of clonal complex 3 strains since 2002. Foodborne Pathogens and Disease, 2011, 8:1169-1176
47. Zhao HX, Chen JS, Fang C, Xia Y, Cheng CY, Jiang LL, Fang WH. Deciphering the biodiversity in Listeria monocytogenes lineage III strains by polyphasic approaches. The Journal of Microbiology, 2011, 49:759-767.
48. Chen JS, Xia Y, Cheng CY, Fang C, Shan Y, Jin GL, Fang WH. Genome sequence of a non-pathogenic Listeria monocytogenes server 4a strain M7. Journal of Bacteriology, 2011, 193:5019-5020.
49. Jiang JJ, Chen JS, Cheng CY, Hu HX, Bai F, Chen N, Yan GQ, Fang WH. Disruption of InlC2 enhances the internalization of Listeria monocytogenes by epithelial cells. World Journal of Microbiology and Biotechnology, 2011, 27: 2155-2161.
50. Bai F, Chen JS, Chen QM, Luo XK, Fang WH, Jiang LL. A single substitution in 50-untranslated region of plcB is involved in enhanced broad-range phospholipase C activity in Listeria monocytogenes strain H4 Acta Biochimica et Biophysica Sinica, 2011, 43:275-283.
51. Shuai JB. Fi LL, Zhang XF, Zhu BL, Li XL< He YQ, Fang WH. Functional exchangeability of the nuclear localization signal (NLS) of capsid protein between PCV1 and PCV2 in vitro: Implications for the role of NLS in viral replication. Virology Journal, 2011, 8:341
52. Chen N, Tong C, Li DJ, Wan J, Yuan XM, Li XL, Peng JR, Fang WH. Antigenic analysis of classical swine fever virus E2 glycoprotein using pig antibodies identifies residues contributing to antigenic variation of the vaccine C-strain and group 2 strains circulating in China. Virology Journal, 2011, 7:378-392.
53. Li XL, Zhu BL, Chen N, Hu HX, Chen JS, Zhang XY, Li J, Fang WH. Molecular characterization and functional analysis of MyD88 in Chinese soft-shelled turtle Trionyx sinensis. Fish & Shellfish Immunology, 2011, 30:33-38.
54. Chen JS, Chen QM, Jiang LL, Cheng CY, Bai F, Mo F, Fang WH. Internalin profiling and multilocus sequence typing suggest four Listeria innocua subgroups with different evolutionary distances from Listeria monocytogenes. BMC Microbiology, 2010, 10:97.
55. Chen N, Li DJ, Yuan XM, Hu HX, Zhu BL, Wan J, Fang WH. Genetic characterization of E2 gene of classical swine fever virus by restriction fragment length polymorphism and phylogenetic analysis. Virus Genes. 2010, 40(3):389-396.
56. Jiang LL, Olesen I, Andersen T, Fang WH, Jespersen L: Survival of Listeria monocytogenes in simulated gastrointestinal system and transcriptional profiling of stress-and adhesion-related genes. Foodborne Pathogens and Disease, 2010, 7(3): 267-274.
57. Chen JS, Chen QM, Jiang JJ, Hu HX, Ye JB, Fang WH. Serovar 4b complex predominates among Listeria monocytogenes isolates from imported aquatic products in China, Foodborne Pathogens and Disease, 2010, 7(1):31-41.
58. Chen XY, Chen Y, Li XL, Chen N, Fang WH. Characterization of surface layer proteins in Lactobacillus crispatus isolate ZJ001. Journal of Microbiology and Biotechnology, 2009, 19(10):1176–1183.
59. Chen JS, Jiang LL, Chen QM, Zhao HC, Luo XK, Chen XY, Fang WH. lmo0038 is involved in acid and heat stress responses and specific for Listeria monocytogenes lineages I and II, and Listeria ivanovii. Foodborne Pathogens and Disease, 2009, 6(3):365-376.
60. Hu HX, Li XL, Zhang ZF, Shuai JB, Chen N, Liu GQ, Fang WH. Porcine reproductive and respiratory syndrome viruses predominant in southeastern China from 2004 to 2007 were from a common source and underwent further divergence. Archive of Virology, 2009, 154:391–398.
61. Chen JS, Jiang LL, Chen XY, Luo XK, Chen Y, Yu Y, Tian GM, Liu DY, Fang WH. Listeria monocytogenes serovar 4a is a possible evolutionary intermediate between Listeria monocytogenes serovars 1/2a and 4b and Listeria innocua. Journal of Microbiology and Biotechnology, 2009, 19(3):238-249.
62. Chen JS, Zhang XF, Mei LL, Jiang LL, Fang WH. Prevalence of Listeria in Chinese food products from 13 provinces between 2000 and 2007 and virulence characterization of Listeria monocytogenes isolates. Foodborne Pathogens and Disease, 2009, 6:7-14.
63. Chen JS, Luo XK, Jiang LL, Jin PJ, Wei W, Liu DY, Fang WH. Molecular characteristics and virulence potential of Listeria monocytogenes isolates from Chinese food systems. Food Microbiology, 2009, 26:103-111.
64. Vongxay K, Wang SN, Zhang XF, Wu BB, Hu HX, Pan ZJ, Cheng SY, Fang WH. Pathogenetic Characterization of Vibrio parahaemolyticus Isolates from Clinical and Seafood Sources. International Journal of Food Microbiology, 2008, 126:71-75.
65. Vongxay K, Pan ZJ, Zhang XF, Cheng SY, Mei LL, XU C, Wang SN, Fang WH. Occurrence of pandemic clones of Vibrio parahaemolyticus isolates from seafood and clinical samples in a Chinese coasting province. Foodborne Pathogens and Disease, 2008, 5(2):127-134.
66. Yang ZZ, Shuai JB, Dai XJ, Fang WH. A survey on porcine circovirus type 2 infeciton and phylogenetic analysis of its ORF2 gene in Hangzhou, Zhejiang Province. Journal of Zhejiang University Science B, 2008, 9(2):148-153.
67. Jiang LL, Chen JS, Xu JJ, Zhang XF, Wang SN, Zhao HC, Vongxay K, Fang WH. Virulence characterization and genotypic analyses of Listeria monocytogenes isolates from food and processing environments in eastern China. International Journal of Food Microbiology, 2008, 21(1): 53-59.
68. Shuai JB, Li XL, Chen N, Chen CY, Fang WH. Characterization and potential use of truncated PCV2 capsid protein and its polyclonal antibody for diagnosis of PCV2 infections. Acta Microbiologica Sinica, 2008:4891):85-90.
69. Shuai JB, Wei W, Jiang LL, Li XL, Chen N, Zhang ZF, Fang WH. Mapping of nuclear localization signals in open reading frame 2 protein from porcine circovirus type 1. Acta Biochimica et Biophysica Sinica (in English), 2008, 40(1):71-77.
70. Li XL, Zhang CL, Fang WH, Lin FC. White-spot disease of Chinese soft-shelled turtles (Trionyx sinens) caused by Paecilomyces lilacinus. Journal of Zhejiang University-Science B, 2008, 9(7):578-581.
71. Chen N, Hu HX, Zhang ZF, Shuai JB, Fang WH. Genetic diversity of the envelope glycoprotein E2 of classical swine fever virus: Recent isolates branched away from historic and vaccine strains. Veterinary Microbiology, 2008, 127:286-299.
72. Shuai JB, Wei W, Li XL, Chen N, Zhang ZF, Chen XY, Fang WH. Genetic characterization of porcine circovirus type 2 (PCV2) from pigs in high-seroprevalence areas in southeastern China. Virus Genes, 2007, 35:619-627.
73. Chen XY, Xu JJ, Shuai JB, Chen JS, Zhang ZF, Fang WH. The S-layer proteins of Lactobacillus crispatus strain ZJ001 is responsible for competitive exclusion against Escherichia coli O157:H7 and Salmonella typhimurium. International Journal of Food Microbiology, 2007,115(3):307-312.
74. Yang ZZ, Habib M, Shuai JB, Fang WH. Detection of PCV2 DNA by SYBR Green I-based quantitative PCR, Journal of Zhejiang University Science B, 2007, 8(3):162-169.
75. Yang ZG, Chen AQ, Sun HX, Ye YP, Fang WH. Ginsenoside Rd elicits Th1 and Th2 immune responses to ovalbumin in mice. Vaccine, 2007, 25(1):161-169.
76. Jiang LL, Ke CL, Xu JJ, Chen JS, Chen XY, Chen N, Shuai JB, Fang WH. Listeria monocytogenes mutants carrying Newcastle disease virus F gene fused to its actA and plcB: In vitro expression and immunogenicity in chickens, Acta Biochimica et Biophysica Sinica (in English), 2007, 39(1):57-66.
77. Varshney M, Li Y, Srinivasan B, Tung S, Erf G, Slavik M, Ying Y, W. Fang. A microfluidics filter biochip based chemiluminescence biosensing method for detection of Escherichia coli O157:H7. Transactions of the ASABE, 2006, 49(6): 2061-2068.
78. Li XL, Shuai JB, Fang WH. Protection of Carassius auratus Gibelio against infection by Aeromonas hydrophila using specific immunoglobulins from hen egg yolk. Journal of Zhejiang University Science B, 2006, 7(11):922-928. (in English)
79. Yang ZZ, Fang WH, Habib M. First Results of Detection of PRRSV and CSFV RNA by SYBR Green I-based Quantitative PCR. Journal of Veterinary Medicine B, 2006;53(10):461-467.
80. Dikki JM, Chen XY, Chen N, Fang WH. Attenuated Salmonella typhimurium as a carrier for prokaryotic and eukaryotic expression vectors. Journal of Zhejiang University (Agric. & Life Sci., ed), 2006, 32(3):237-244. (in English).
81. Li L, Fang WH, Li JR, Huang YW, Yu L. Oral DNA vaccination with the polyprotein gene of infectious bursal disease virus (IBDV) delivered by attenuated Salmonella elicits protective immune responses in chickens. Vaccine, 2006, 24(33-34):5919-5927.
82. Fang WH, Budde B; Siegumfeldt H. Leucocins 4010 from Leuconostoc carnosum cause a matrix related decrease in intracellular pH of Listeria monocytogenes, FEMS Microbiology Letters, 2006, 258(2): 208-213.
83. Jiang LL, Xu JJ, Chen N, Shuai JB, Fang WH. Virulence phenotyping and molecular characterization of a low-pathogenicity Listeria monocytogenes isolate from milk, Acta Biochimica et Biophysica Sinica (in English), 2006, 38(4):262-270
84. Vongxay KP, Cheng SY, Zhou XY, Shen B, He X L, Zhang GZ, Fang WH* Prevalence of Vibrio parahaemolyticus in seafoods and their processing environments as detected by Duplex PCR. Journal of the Science of Food & Agriculture, 2006, 86(12): 1871-1877..
85. Zeng HY, Zhang XF, Sun Z, Fang WH. Multiplex PCR identification of Listeria monocytogenes isolates from milk and milk-processing environments. Journal of the Science of Food & Agriculture, 2006, 86(3):367-371.
86. Yang ZG, Sun HX, Fang WH. Haemolytic activities and adjuvant effect of Astragalus membranaceus saponins (AMS) on the immune responses to ovalbumin in mice. Vaccine, 2005, 23 (44): 5196-5203.
87. Ke CL, Song HH , Jiang LL, Zeng HY, Zhang GZ, Fang WH. Construction of the recombinant Listeria monocytogenes mutant expressing green fluorescent protein. Journal of Zhejiang University (Agric. & Life Sci., ed), 2005, 31(5): 638-644. (in English)
88. Jiang LL, Song HH, Chen XY, Ke CL, Xu JJ, Chen N, Fang WH. Characterization of a Mutant Listeria monocytogenes Strain Expressing Green Fluorescent Protein. Acta Biochimica et Biophysica Sinica (in English), 2005, 37(1): 19–24.
89. Song HH, Fang WH, Wang ZL et al. Detection of foot-and-mouth virus antibodies using a purified protein from the high-level expression of codon-optimized, foot-and-mouth disease virus complex epitopes in Escherichia coli. Biotechnology Letters, 2004, 26(16):1277-1281.
90. Fang WH, Siegumfeldt H, Budde BB, Jakobsen M. Osmotic stresses led to decreased intracellular pH of Listeria monocytogenes as analyzed by fluorescence ratio-imaging microscopy. Applied & Environmental Microbiology, 2004, 70(5):3176-3179.
91. Song HH, Li Y., Fang WH, Geng YF et al. Development of a set of expression vectors in Hansenula polymorpha. Biotechnol. Lett., 2003, 25:1999-2006.
92. Zhong BX, Weng HB, Fang WH. Preparation of protein samples for gel electrophoresis by sequential extraction. Journal of Zhejiang University, Science ed. (in English), 2002, 3(5):606-610.
93. Fang WH, Almeida R.A., Oliver S.P. Effects of lactoferrin and milk on adherence of Streptococcus uberis to bovine mammary epithelial cells. American Journal of Veterinary Research,, 2000, 3:275.
94. Fang WH., Oliver S. P. Identification of lactoferrin-binding proteins from bovine mastitis causing Streptococcus uberis. FEMS Microbiology Letters, 1999, 176:91.
95. Almeida R.A., Fang W., Oliver S.P. Adherence and internalization of Streptococcus uberis to bovine mammary epithelial cells are mediated by host cell proteoglycans. FEMS Microbiology Letters, 1999, 177:313.
96. Fang WH., Luther D. A., Oliver S. P. Protein expression by Streptococcus uberis in co-culture with bovine mammary epithelial cells. FEMS Microbiology Letters, 1998, 166:237.
97. Fang WH., Luther D. A., Almeida R. A., Oliver S. P. Decreased growth of Streptococcus uberis in milk from mammary glands of cows challenged with the same mastitis pathogen. Journal of Veterinary Medicine B, 1998, 45:295.
98. Ali-Vehmas T., Vikerpuur M., Fang WH., Sandholm M. Giving selenium supplements to dairy cows strengthens the inflammatory response to intramammary infection and induces a growth-suppressing effect on mastitis pathogens in whey. Journal of Veterinary Medicine A, 1997, 44:559.
99. Fang WH., Myllys V., Sandholm M. Resazurin reduction as a function of respiratory burst of bovine polymorphonuclear neutrophils. American Journal of Veterinary Research, 1997, 58(6):601.
100. Fang WH. Novel fluorometric methods for evaluation of phagocytosis, potency and postantibiotic effect of antibacterials in milk. PhD thesis, 1996, Helsinki University, Helsinki, Finland.
101. Fang WH. A novel fluorometric method for evaluation of postantibiotic effect on mastitis-causing Staphylococcus aureus and Escherichia coli. Journal of Microbiological Methods, 1996, 26:151.
102. Fang WH. Quantification of Staphylococcus aureus and Escherichia coli in the liquid medium by fluorometry and its use in phagocytosis assay. Journal of Applied Bacteriology, 1996, 80:577.
103. Koivunen A-L., Maisi P., Fang WH., Sandholm M. Inhibition of the protease activity in tracheobronchial aspirates of horses with COPD. American Journal of Veterinary Research, 1996, 57(5):603.
104. Malbe M., Salonen M., Fang WH., Oopic T., Jalakas M., Klaassen M., Sandholm M. Disposition of enrofloxacin (BaytrilR) into the udder after intravenous and intra-arterial injections. Journal of Veterinary Medicine A, 1996, 43:377.
105. Fang WH., Vikerpuur M., Sandholm M. Reconstitution of mastitic milk by adding blood plasma and leukocytes into low cell count milk. Veterinary Research (France), 1996, 27:33.
106. Fang WH., Shi M., Huang L., Chen J. Antagonism of the lactic acid bacteria towards Staphylococcus aureus and Escherichia coli on the agar plates and in milk. Veterinary Research (France), 1996, 27:3.
107. Fang WH., Pyorala S. Mastitis-causing Escherichia coli: Serum sensitivity and susceptibility to selected antibacterials in milk. Jouranl of Dairy Science, 1996, 79:76.
108. Fang WH., Vikerpuur M. Potency of antibacterial drugs in milk as analyzed by the ß-glucuronidase-based fluorometry. Journal of Veterinary Pharmacology & Therapeutics, 1995, 1:422.
109. Fang WH., Vikerpuur M., Sandholm M. A fluorometric ß-glucuronidase assay for analysis of bacterial growth in milk. Veterinary Microbiology, 1995, 46:361.
110. Malbe M., Klaassen M., Fang WH., Myllys V., Vikerpuur M., Nyholm K., Sankari S., Suoranta K., Sandholm M. Comparison of selenite and selenium yeast feed supplements on Se-incorporation, mastitis and leukocyte function in Se-deficient dairy cows. Journal of Veterinary Medicine A, 1995, 42:111.
111. Fang WH, Sandholm M. Inhibition of the proteinase activity in mastitic milk. Journal of Dairy Research, 1995, 64:61.
112. Fang WH., Shi M., Chen J., Huang L. & Shao Q. Comparative aspects of bacterial growth in milk and whey. Chinese Veterinary Science (English), 1994, 1(1):32.
113. Fang WH., Shi M., Chen J., Huang L. & Shao Q. Turbidometric determination of bacterial growth in whey. Chinese Journal of Veterinary Science (English), 1994, 1(1):28.
114. Fang WH., Shi M., Huang L. & Shao Q. Growth of lactic acid bacteria, Staphylococcus aureus and Escherichia coli in normal and mastitic milk and whey. Veterinary Microbiology, 1993, 37:115.
115. Fang WH., Jiang C. & Liu H. Epidemiological aspects of bovine mastitis and its control in several dairy herds in south-east China. Preventive Veterinary Medicine, 1993, 15(2-3):169.
116. Hu SH, Fang WH, Lu HR, et al. Effect Of Teat Dipping And Dry Cow Therapy On Mastitis In A Commercial Dairy-Herd In China. Preventive Veterinary Medicine, 1990, 10:(1-2), 91-96.

       1.  The Bovine Udder and Mastitis，芬兰赫尔辛基大学出版社 1995，参编

       2.  汉英中兽医辞典（修订版），中国农业出版社2003，编者

       3.  兽医公共卫生学，中国农业出版社2003，副主编

       4.  动物性食品卫生学，高等教育出版社 2005，参编

       5.  食品检验检疫学，中国农业出版社2007，副主编

 特邀或会议报告：