PERSONEL
Ji-Yong Zhou, D.V.M, MS, Ph.D.
Born on
Address: Laboratory of Veterinary Virology and Immunology,
Tel: +86 571 8697 1698
Fax: +86 571 8697 1821
Email: jyzhou@zju.edu.cn
ACADEMIC DEGREE AND SCIENTIFIC BACKGROUND
1980-1984 D.V.M. Sichuan Institute of Animal Husbandry and Veterinary Medicine, China.
1986-1989 M.S. Veterinary
1997-1999 Ph.D.
PRESENT POSITION
Vice director, Zhejiang University Institute of preventive veterinary medicine, 1999-
Professor of Virology and Immunology,
Associate Professor of Virology and Immunology,
REREARCH INTERESTS
Molecular Virology and Immunology
PROFESSIONAL ORGANIZATIONS
Chinese Society of Immunology
Society of Poultry Diseases, Chinese Association of Animal Science and Veterinary Medicine.
Biotechology Society, Chinese Association of Animal Science and Veterinary Medicine
Veterinary Microbiology Society, Chinese Association of Microbiology.
HONORS and RESEARCH AWAREDS
2003 Outstanding Scientist of
2002 Personal Program of New century ?°151?± in
2002 Recipient of the First Award on Science and Technology from Zhejiang Provincial Government of Province entitled in ?°Studies on DNA Immunization against Infectious Busal Disease Virus?±
2002 Recipient of the Second Award on Science and Technology from Zhejiang Provincial Government of Province entitled in ?°Molecular Identification and Control on a New Infectious Bronchitis?±
2000 Recipient of the Second Award on Science and Technology from Zhejiang Provincial Government of Province entitled in ?°Study on attenuated vaccine of infectious bursal disease virus variants?±
2000 Recipient of the Second Award on Science and Technology from Zhejiang Provincial Government of Province entitled in ?°Expression and Immunogenecity of Infectious Busal Disease Virus Main Host Antigen in E.coli. and Silkworm?±
1994 Recipient of the Third Award on Science and Technology from Sichuan Provincial Government of Province entitled in ?°Isolation, Pathologenesis, Prevention on Infectious Bursal Disease Virus in
2004-2008 Science Advisor, The People??s Government of Wanzhou district,
RESEARCH GRANTS
2005-2007 Cloning of Chicken Interleukin 2 Receptor and Its Characterization (National Natural Science Foundation of
2004-2006 New Type Engineering Vaccine Against infectious Bronchitis Virus (Key project, Department of Science and Technology, Provincial Government of Zhejiang,
2004-2005 Sero-ecology of Avian Influeza Virus in Wildlife animals (Ministry of Science and technology,
2004-2006 Avian Cytokine and DNA Immunization against IBV (Outstanding Young Fund,
2004-2006 Biological Function of Proteins Encoded by Some ORFs within Genome of Porcine Circovirus Type II (National Natural Science Foundation of
2003-2006 Key Preventive Techniques of Swine Immunodeficiency Diseases (Key project, Department of Science and Technology, Provincial Government of Zhejiang,
2003-2005 Plant-Edible Vaccine against IBV (Education Ministry of
2003-2006 Molecular Pathogenesis and Immune Mechanism of Infectious Bursal Disease Virus (Key project, National Natural Science Foundation of China)
2001-2003 Expression of S1 Gene of Avian Infectious Bronchitis Virus in Transgenic Potato (National Natural Science Foundation of
2000-2002 Analysis of Structural protein and Genomic Structure of a New Chicken??s Coronavirus (National Natural Science Foundation of China)
2000-2002 Biological Characteristics of a variant Infectious Bronchitis Virus (
1999-2001 Divergences of Variant Infectious Bursal Disease Virus (
1997-1999 Studies on Serotypes and Immunogenicity of Avian Infectious Bronchitis Nephritis Virus (
1996-2000 Isolations of Variant Infectious Bursal Disease Virus and Control of Infectious Bursal Disease In
1999-2002 Identifications on Chicken Infectious Proventriculitis and its Control (Key project, Department of Science and Technology, Provincial Government of Zhejiang,
2001-2005 Cloning of Avian interleukin-2 (Bureau of Science and Technology, City Government of Hangzhou, China)
STUDENT SUPERVISING
PATENT
Zhou JY et al. Production of Recombinant Chicken Interleukin 2 protein. A patent applied by State Intellectual Property Office of P.R.C., 031505527.9
Zhou JY et al. Production of Recombinant Duck Interleukin 2 protein. A patent applied by State Intellectual Property Office of P.R.C., 200310108658.6
Zhou JY et al. Production of Recombinant Goose Interleukin 2 protein. A patent applied by State Intellectual Property Office of P.R.C., 200310108622.8
Zhou JY et al. Indirect Antibody-detecting ELISA of Porcine Circovirus type II . A patent applied by State Intellectual Property Office of P.R.C., 200410066998.1
Zhou JY et al. Antigen-detecting ELISA of Porcine Circovirus type II . A patent applied by State Intellectual Property Office of P.R.C., 200410025286.5
Zhou JY et al. DNA Vaccine of Porcine Circovirus type II. A patent applied by State Intellectual Property Office of P.R.C., 200410018525.8
Zhou JY et al. Indirect Antibody-detecting strip of Porcine Circovirus type II . A patent applied by State Intellectual Property Office of P.R.C., 200410025288.4
BOOKS And CHAPTERS
Ji-Yong Zhou, 1992. Techniques of Modern Animal Pathology.
Ji-Yong Zhou, 1996. Poultry Disease. In: Yao-Qian Pan, Veterinary Pathology.
Ji-Yong Zhou, 1998. Poultry Infectious Diseases. In: Yong-zheng Lin, Veterinary Epidemiology.
Ji-Yong Zhou, 2003. Complement. In: Han-Chun Yang, Textbook of Veterinary Immunology.
PUBLICATIONS
1. Zhou JY, Ye JX, Zheng XJ, Guo JQ. 2004. Characterization of subtype isolates of infectious bursal disease virus in
2. Zhou JY, Chen QX, Ye JX, Shen HG, Chen TF, Shang SB. 2004. Serologic investigation and genomic characterization of PCV2 isolates from different geographic regions of
3. Zhou JY, Wang JY, Chen HG, Wu JX, Gong H, Teng QY, Guo JQ, Shen HG. 2004. Cloning, in vitro expression and bioactivity of duck interleukin-2. Mol. Immunol. (In press)
4. Guo JQ, Chen L, Ai HW, Jing JN, Zhou JY, Zhang CY, You SY. 2004. A Novel Fusion Protein of IP10-scFv Retains Antibody Specificity and Chemokine Function. Biochem. Biophys. Res. Commun. 320: 506-513 (PDF)
5. Zhou JY, Zhang DY, Ye JX, Cheng LQ. 2004. Characterization of an Avian Infectious Bronchitis Virus Isolated in
6. Zhou JY, Cheng LQ, Zheng XJ, Wu JX, Shang SB, Wang JY, Chen.JG. 2004. Generation of the transgenic potato expressing full-length spike protein of infectious bronchitis virus. J. Biotechnol. 111??121-130 (PDF)
7. Zhou JY, Wu JX, Cheng LQ, Zheng XJ, Gong H, Shang SB, Zhou EM. 2003. Expression of Immunogenic S1 Glycoprotein of Infectious Bronchitis Virus in Transgenic Potatoes. J. Virol. 77?¨16????9090-9093 (PDF)
8. Zhou JY, Chen JG, Wang JY, Kwang J. 2003. Cloning and Genetic Evolution Analysis of chIL-2 Gene of Chinese Local Breeds. Prog. Biochem. Biophys. 30(3): 384-389?¨PDF??
9. Wu JX, Zhou JY(Corresponding author), Zhou XP. 2003.Transgenic potato containing immunogenic gene of avian coronavirus and its immunogenicity in mice. Acta Bioch Bioph Sin. 35(11): 1011-1015. (PDF)
10. Chen QX, Zhou JY, Ye JX, Shen HG, Chen TF. 2004. Isolation and genomic structure of Porcine circovirus type II in
11. Zhou JY, Chen QX, Ye JX, Zhu JX, Zheng XJ, Shang SB, Chen TF, Mu AX, Zhou EM. 2004. Serological investigation of porcine circovirus 2 infection. Chin. J. Vet. Sci. 24(1):1-3 (PDF)
12. Cheng LQ, Zhou JY, Dikki J, Shen XY, Chen JG, Zhang DY. 2003. Molecular Characteristics of S1 Gene of Infectious Bronchitis Virus Isolated from Chicken Proventriculus. Agri. Sci.Chin. 36?¨10??: 1028-1332 (PDF)
13. Wang JY, Zhou JY, Chen JG, Zhang ZH, Teng QY. 2003. Cloning and Genetic Evolution Analysis of like Avian Interleukin 2 Gene in Ducks. Chin. J. Vet. Sci. 23(6): 545-547 (PDF)
14. Wang XN, Zhou JY, Yang YY, Xing GX, Yang JF, Zi SJ, Zhao D, Kang XD, Zhang GP. 2003. Establishment of Resisting Clenbuterol Monoclonal Antibodies Hybridoma and Characteristic Identification of Hybridoma excreted Monoclonal Antibodies. Chin. J. Immunol. 19(12): 101-105. (PDF)
15. Zhou JY, Zhang DY, Ding HM, Cheng LQ. Chen JG. 2003. Genetic Variance Analysis of Nucleocapsid Protein Gene of Infectious Bronchitis Viruses with Different Tissue Tropism. Chin. J. Viol. 19(1): 63-67 (PDF)
16. Zhou JY, Ding HM, Cheng LQ, Kwang J. 2003. Variation of Nucleocapsid Protein Gene of Infectious Bronchitis Virus and its Expression in Escherichia coli. J.
17. Chen JG, Zhou JY, Zheng XJ. 2003. Cloning and Genetic Analysis of Interleukin 2 Gene in Silky Chicken of Chinese Local Breed. Chin. J. Prev. Vet. Med. 25(5): 21-23 (PDF)
18. Zhou JY, Chen JG, Wang JY, Zhang DY, Zheng XJ. 2003. Expression of chicken interleukin-2 gene in Pichiamethanolica. J.
19. Chen JG, Zhou JY, Wang JY, Cheng LQ, Chen QX, Ye JX, Zheng XJ, Shang SB. 2003. Cloning and Secondry Structure Analysis of Interleukin 2 Gene in AVIAN Briorer Chickens. Chin. J. Vet. Sci. Tech. 33(1): 19-24 (PDF)
20. Chen QX, Shang SB, Ye JX, Mu AX, Wang YF, Lu GL, Zhou JY. 2003. The Serology Investigation of PCV II Antibody in
21. Zhou JY, Ding HM, Cheng LQ, Shen XY. 2002. Cloning of Nucleocapsid Gene of Infectious Bronchitis Virus and Its Expression in E.coli. Chin. J. Biochem. Mol. Biol. 18(4): 450-455 (PDF)
22. Zhou JY, Cheng LQ, Shen XY, Ding HM, Wu JX. 2002. Cloning of Sequencing of S gene of Novel Variant of Infectious Bronchitis Virus ZJ971 Isolates in
23. Zhang DY, Zhou JY, Chen JG, Ding HM, Shen XY. 2002. Cloning and Sequence Analysis of Nucleocapid Gene of X-Strain of Nephripathogenic Infectious Bronchitis Virus. Chin. J. Vet. Sci. 22(6): 529-532 (PDF)
24. Zhang DY, Zhou JY, Chen JG. 2002. The Study Progress of Antisense Nucleic Acid. Chin. J. Prev. Vet. Med. 24(2): 158-160 (PDF)
25. Shen XY, Zhou JY, Ding HM, Wu JX, Yan QF. 2001. Cloning and Sequencing of S2 Gene of Avian Proventriculopathic Infectious Bronchitis Virus Chinese Isolate ZJ971. Chin. J. Vet. Sci. 21(6): 540-543 (PDF)
26. Ding HM, Zhou JY, Shen XY, Wu JX, Cheng LQ, Yu L. 2001. Cloning of Nucleocapsid Protein Gene of Proventriculopathic Infectious Bronchitis Virus ZJ971 Isolate. J of Agri. Biotech. 9(3): 243-246 (PDF)
27. Wu JX, Zhou JY, Cheng LQ, Shen XY, Ding HM. 2002. The construction of plant expression vector of S1 gene of avian infectious Bronchitis Virus. J.
28. Wu JX, Zhou JY, Yu C. 2002. The Gene Engineer Vaccines expressed by Transgenic Plant. Chin. J. Prev. Vet. Med. 23?¨2????157-159 (PDF)
29. Ding HM, Zhou JY, Yu L. 2001. Molecular Biology of Nucleocapsid gene for Infectious Bronchitis Virus. Prog. Prev. Vet. Med. 3(2):1-4
30. Chen JG, Zhou JY, Zhang DY. 2001. The Reviews of Avian Interleukin 2. Prog. Vet. Med. 22(4): 36-40 (PDF)
31. Zhou JY. 2000. Biological Characteristics of Infectious Proventriculitis Virus (IPV) ZJ971 Isolate. Acta Veterin. Zootech. Sin. 31(3): 227-234 (PDF)
32. Zhou JY. 2000. Pathogenicity of Infectious Proventriculitis Virus (Tentative Name) in Chickens. Chin. J. Vet. Sci. 20(2): 124-127 (PDF)
33. Zhou JY, Li JR. 2000. Genetic Stability and Immunogenicity of Attenuated Infectious Bursal Disease Virus Variants. Chin. J. Vet. Sci. 20(4): 317-320 (PDF)
34. Zhou JY. 2000. S1 gene of Infectious Bronchitis Virus (ZJ971 Isolate) and Its Structural Proteins. Chin. J. Vet. Sci. 20(5): 429-433 (PDF)
35. Zhou JY, Li JR. Study on Bivalent Attenuated Vaccine of Infectious Bursal Disease Virus Variants. J.
36. Zhou JY, He YQ. 2000. Cloning and Sequence Analysis of S1 Gene of Isolate J of Avian Nephropathogeic Infectious Bronchitis Virus. J.
37. He YQ, Zhou JY, Yu L. 2000. Restriction fragment length polymorphism analysis of
38. Li JR, Zhou JY. 2000. Attenuation of Variant Strains of Infectious bursal Disease Virus. Chin. J. Prev. Vet. Med. 22?¨4????255-258 (PDF)
39. Li JR, Zhou JY. 2000. Immunogenicity of Attenuated Variant Strains of infectious bursal Disease Virus. Chin. J. Prev. Vet. Med. 22(5): 347-351 (PDF)
40. Li JR, Yu L, Zhou JY, 2000. Zheng XX. Molecular Epidemiology of Infectious Bursal Disease Virus. Chin. J. Vet. Sci. Tech. 30(7): 16-18 (PDF)
41. Li JR, Zhou JY, Yu L. 2000. Reviews on Vaccines of Infectious Bursal Disease Virus Variants. Prog. Prev. Vet. Med. 2(1): 7-10
42. Zhang ZY, Zhou JY. Effection of IL-12 and IL-10 to Virus Replication and T Cell Apoptosis of Feline Immunodeficiency Virus Infected. Prog. Vet. Med. 2000. 21(1): 59-60 (PDF)
43. Zhang ZY, Yu L, Zhou JY. 2000. Retrospective investigation of Monoclonal Antibodies to Infectious Bursal Disease Virus. Prog. Prev. Vet. Med. 2(1): 27-30.
44. Huang YW, Yu L, Zhou JY. 2000. Advances in study of circadian clock mechanism. Life Science. 12(1): 10-13 (PDF)
45. Zhou JY, Ye WC, Yu L. 1999. Isolation and Identification of Field Infectious Bursal Disease Virus Variants from
46. Zhou JY, Ye WC, Yu L. 1999. Physicochemical Properties of Field Infectious Bursal Disease virus isolates from
47. Zhou JY, Ye WC, Yu L. 1999. Serosubtype Analysis of Field Infectious Bursal Disease Virus Isolates. Chin. J. Prev. Vet. Med. 21(1): 53 ¨C55 (CAJ)
48. He YQ, Zhou JY, Yu L, Sheng ZT. 1999. Application of Monoclonal Antibodies to FMDV. Prog. Prev. Vet. Med. 1(2): 19-22
49. Zhou JY, Yu L, Hong J, Ye WC, Zhang ZY. 1998. Isolation of Avian Infectious Proventriculitis. J. Zhejiang Agri. Univ. 24(6):637-641 (CAJ)
50. Zhou JY, Yu L, Ma YZ. 1998. Isolation and Identification of Chicken??s Infectious Bronchitis Nephritisvirus. J. Zhejiang Agri. Univ. 24(3): 303-307 (CAJ)
51. Zhou JY, Tan X, Li JX, Zhu ZF. 1995. Isolation and Determination of Ophthalmitis Pathogen in Fowl. Chin. J. Livest. Poult. Epidemiol. 17(2): 8-11 (VIP)
52. Li JX, Zhou JY, Zhu ZF. 1995. Diagnosis on Avian Staphylococcus Dermatitis.
53. Zhou JY, Zhong P, Liu YX, Li JX, Zhu ZF. 1994. Isolation and Identification of Chicken??s Egg Drop Syndrome (EDS-76) Virus. Chin. J. Livest. Poult. Epidemiol. 16(2): 5-9 (VIP)
54. Zhou JY, Zhu ZF. 1994. Studies on Oil-Emulsion Inactivated Vaccine against Infectious Bursal
55. Zhou JY, Su FX, Gan YH, Zhu ZF. 1994. Studies on Oil-Emulsion Inactivated Vaccine against Infectious Bursal Disease II. Antibody Change and Immunocytomorphology. Chin. J. Livest. Poult. Epidemiol. 16?¨4????15-18 (VIP)
56. Zhou JY, Yu GH. 1994. Reviews on Avian E.coli Infections.
57. Zhou JY, Li JX, Zhu ZF, Song XK, Xiao XC. 1994. Immune Programme Investigation of Infectious Busal Disease in Chicken Farm Contaminated by IBDV. J.
58. Zhou JY, Li XM, Nie K, Tang FS, Zeng ZJ, Li AX. 1993. Studies on Pathology of Exeperimental Cryptoridiosis in Young Ducks. Acta Veterin. Zootech. Sin. 24(1): 67-73 (VIP)
59. Zhou JY, Zhu ZF, Li JX et al. 1993. Prepration and Application of High Immune Yolk Liquid to Resist Infectious Bursal Disease.
60. Zhou JY, Yang YP, Li JX, Zhu ZF. 1993. Isolation and Identification of Chick Pathogenic E.coli. in
61. Zhou JY, Zhu ZF, Wei YC, Ye HH, Zhao P. 1993. Immune Programme Investigation of Infectious Bursal Disease Virus.
62. Zhou JY. 1991. Isolation, Identification and Physicochemical Characteristics of Infectious Bursal Disease Virus from
63. Tang M, Zhou JY, Zeng ZJ, Tang FS. 1990. An Outbreak of Infectious Busal Disease in
64. Zhou JY, Huang W, Tang FS. 1990. Diagnosis on Septic Swine Erysipelas. J.Sichuan Ins. Ani. Hus. Vet. Med. 4(2-3): 83-84
65. Zhou JY, Qiu ZD. 1990. Pathological Studies on Infectious Busal Disease.I. Immunopathomorphology of Chickens artificially infected by IBDV. J.
66. Zhou JY, Qiu ZD. Pathological Studies on Infectious Busal Disease. I. Immunomorphology of Attenuated Live IBDV Vaccine. J.
67. Li AX, Nie K, Zhou JY, Zeng ZJ. 1990. Cryptosporidium in
CONFERENCE PAPERS
68. Zhou JY, Cheng LQ, Shen XY, Ding HM, Wu JX. 2000. Structural proteins and cloning of S gene of isolate ZJ971 of avian novel variant of infectious bronchitis virus in
69. Zhou JY, Li JR, Ye WC, Yu L. 2000. Pathogenicity and immunogenicity of attenuated infectious bursal disease virus variants from
70. Zhou JY, Cheng LQ, Shen XY, Ding HM, Wu JX. 2001. Pathogenicity and cloning of S gene of isolate ZJ971 of avian novel variant of infectious bronchitis virus in china. Proceedings XII International Congress of the World Veterinary Poultry Association,
71. Zhou JY, Cheng LQ, Shen XY, Ding HM, Wu JX. 2001. Variation in the nucleocapsid protein genes of infectious bronchitis virus with different tissue tropism. Proceedings XII International Congress of the World Veterinary Poultry Association,