基本信息

教育背景与工作简历

1960.09－1965.07　浙江农业大学畜牧兽医系　本科生

1965.08－1979.08　浙江省海盐县农业局

1979.09－1982.07　浙江农业大学畜牧兽医系　研究生

1982.08－1987.06　浙江农业大学畜牧兽医系　讲师

1987.07－1988.12　美国弗吉尼亚州立理工大学      访问学者

1989.01－1991.07　浙江农业大学饲料科学研究所　副教授、所长　

1991.08－2006.05　浙江(农业)大学饲料科学研究所　教授、所长

1998.09－2005.05　浙江大学动物科学学院　常务副院长、教授、博导；浙江大学饲料科学研究所　 所长

2006.06－浙江大学饲料科学研究所      教授、博导

学术兼职

1. 中国畜牧兽医学会动物生理生化分会副理事长；

2. 美国动物科学学会和家禽学会会员；

3. 养猪学分会常务理事；

4. 动物营养学分会理事；

5. 中国养猪学报、浙江农业学报副主编；

6. 东北农业大学、云南农业大学、苏州大学、绍兴文理学院兼职教授；

7. 云南农大饲料与动物营养省重点实验室副主任。

所获荣誉与主要奖励

荣誉

1. 教育部对口支援西部先进个人

2. “各民主党派、工商联、无党派人士为全面建设小康社会作贡献”全国先进个人

3. 国家有突出贡献中青年专家

4. 全国五一劳动奖

5. 作出突出贡献的中国硕士学位获得者

6. 全国农业科技先进工作者

7. 全国饲料工业科技进步先进个人

8. 全国饲料工业行业先进工作者

9. 浙江省重大科技贡献一等奖获得者

10. 浙江省农业科技突出贡献者

11.浙江省劳动模范

12. 享受政府特殊津贴

奖励

1. 2000年，高效转化、肉质改良、资源开发型全价饲料的研发与产业化　国家科技进步二等奖

2. 2002年，用酶技术开发大麦及高麸饲粮及其产业化研究　　国家科技进步二等奖

3. 1994年，畜禽全价饲料及其添加剂开发　　浙江省星火一等奖

4. 1991年，浙农一号猪用系列全价配合饲料研制　　浙江省科技进步一等奖

5. 1990年，菜籽饼解毒添加剂“6107”推广应用　　国家教委科技进步一等奖

6. 2005年，高效消除饲料中重金属、黄曲霉毒素的纳米级添加剂研发与产业化　浙江省科技进步二等奖

7. 2004年，改善畜禽肉质的营养调控技术研究及产业化　　浙江省科技进步二等奖

8. 2001年，野生风味甲鱼全价配合饲料的研制　　浙江省科技进步二等奖

9. 2000年，应用酶工程提高大麦和糠麸饲用价值及产业化研究　　浙江省科技进步二等奖

10. 1998年，新型畜禽营养再分配剂研制及产业化技术研究　　浙江省科技进步二等奖

11. 1993年，浙农一号肉禽系列全价配合饲料　　浙江省科技进步优秀奖

专利
1. 以纳米蒙脱石为载体的畜禽消毒剂及其制备方法

2. 吸附饲料中霉菌毒素的纳米饲料添加剂的制备方法

3. 高效纳米级水质净化剂及其制备方法

4. 去除养殖水体中磷和亚硝态氮的铁改性蒙脱石制备方法

5. 甜菜碱盐酸盐的合成方法

6. 里氏木霉菌株及其用途

研究领域

介观生物学与动物营养、营养与动物产品安全和品质

完成及现有课题

1．饲料玉米赤霉烯酮吸附-降解剂(ZAD)的研制与产业化　科技厅(重点)2006-2008

2．中国西南喀斯特山区高效生产优质牛奶牛肉配套技术研究及产业化　科技部(重大) 2002-2005

3．甲基氨基酸促进猪GH基因表达的机理及应用研究　国家基金1999-2001

4．纳米级载铜硅酸盐吸附、杀灭大肠杆菌K88机理的研究　国家基金2005-2007

5．猪生长基因表达促进剂　科技部2000-2002

6．畜禽肉质改良剂的研制及产业化技术　科技部2000-2002

7．β-葡聚糖酶和木聚糖酶中试及产业化　教育部2000-2001

8．纳米级微粒型对氨基苯胂酸的抗菌、抗球虫效果及机理　教育部

9．猪生长基因表达促进剂　省科技厅2000-2001

10．改善畜禽肉质的营养调控技术研究与开发　省科技厅2000-2002

11．高效消除饲料中重金属、黄曲霉毒素的纳米级添加剂研发与产业化　省科技厅2002.9-2003.12

12．甲鱼全价饲料的研制和应用　省科技厅1996-2002

13．改善畜禽肉质预混料中试　省科技厅2002-2003

14．通过营养调控基因表达提高猪鸡肉质的研究　省基金（重点）2000-2002

15．亮氨酸对肥育猪背最长肌蛋白质合成的影响及作用机理　省基金1999-2001

16．高效、优质、环保型系列饲料添加剂　横向(重大)2002-2003

17．b-葡聚糖酶和木聚糖酶基因工程菌的构建及产业化　横向(重大)2002-2003

18．纳米级添加剂和水质净化剂开发推广　横向(重大)2002-2003

19．抗癌新药――“普爱I号”研发. 横向(重大). 2006-2008

学术论文

1. Zhang WJ, Xu ZR,Sun JY, Yang X. Effect of selected fungi on the reduction of gossypol levels and nutritional value during solid substrate fermentation of cottonseed meal. Journal of Zhejiang University Science B, 2006, 7(9): 690-695

2. Han XY, Xu ZR, Wang YZ, et al.Effects of cadmium on serum sex hormone levels in pigs. JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION 90 (9-10): 380-384 OCT 2006

3. Zhang WJ, Xu ZR, Zhao SH, et al.Optimization of process parameters for reduction of gossypol levels in cottonseed meal by Candida tropicalis ZD-3 during solid substrate fermentation.TOXICON 48 (2): 221-226 AUG 2006

4. Wang YB, Zhang WJ, Li WF, Xu ZR.Acute toxicity of nitrite on tilapia (Oreochromis niloticus) at different external chloride concentrations .FISH PHYSIOLOGY AND BIOCHEMISTRY 32 (1): 49-54 MAR 2006

5. Zhang WJ, Xu ZR, Sun JY, et al. A study on the reduction of gossypol levels by mixed culture solid substrate fermentation of cottonseed meal .ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 19 (9): 1314-1321 SEP 2006

6. Shi YH, Xu ZR, Feng JL, et al.Efficacy of modified montmorillonite nanocomposite to reduce the toxicity of aflatoxin in broiler chicks.ANIMAL FEED SCIENCE AND TECHNOLOGY 129 (1-2): 138-148 AUG 4 2006

7. Qi LF, Xu ZR In vivo antitumor activity of chitosan nanoparticles. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16 (16): 4243-4245 AUG 15 2006

8. Jha R K, Xu ZR, Shen J, Bai SJ, Sun JY, Li YF. The efficacy of recombinant vaccines against white spot syndrome virus in Procambarus clarkii. Immunology Letters 2006; 105:68-76                                                                                                                         

9. Wang F, Xu ZR, Su JH. Effect of HCH contamination of diet on the growth performance and immune and antioxidant ability in growing/finishing pigs VETERINARY RESEARCH COMMUNICATIONS 2006, 30 (6): 645-654 

10. Han XY, Xu ZR, Wang YZ, Huang QC. Effect of Cadmium on Lipid Peroxidation and Activities of Antioxidant Enzymes in Growing Pigs. Biol. Trace Ele. Res. 2006, 110 (3): 251-263

11. Tao X, Xu ZR, Wang YZ. Effects of dietary fluoride levels on growth, serum indexes and antioxidant systems in growing pigs TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES 2006,30 (1): 65-70 

12. Xu ZR, Du HH, Xu YX, et al. Crayfish Procambarus clarkii protected against white spot syndrome virus by oral administration of viral proteins expressed in silkworms. AQUACULTURE, 2006, 253 (1-4): 179-183 

13.Wang YB, Xu ZR. Effect of probiotics for common carp (Cyprinus carpio) based on growth performance and digestive enzyme activities ANIMAL FEED SCIENCE AND TECHNOLOGY, 2006, 127 (3-4): 283-292 

14. Wang L, Xu ZR, Jia XY, et al. Effects of arsenic (As-III) on lipid peroxidation, glutathione content and antioxidant enzymes in growing pigs. ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 2006,19 (5): 727-733 

15. Ma YL, Guo T, Xu ZR, et al. Effect of Lactobacillus isolates on the adhesion of pathogens to chicken intestinal mucus in vitro LETTERS IN APPLIED MICROBIOLOGY 2006,42 (4): 369-374 

16. Jiang JF, Xu ZR, Wang YZ, et al. Postnatal expression pattern of the C/EBP alpha gene in porcine subcutaneous adipose tissue JOURNAL OF ANIMAL AND FEED SCIENCES 2006, 15 (1): 61-70

17. Yu DY, Xu ZR, Yang XG In vitro, in vivo studies of Cu(II)-exchanged montmorillonite for the removal of lead (Pb) ANIMAL FEED SCIENCE AND TECHNOLOGY 2006,127 (3-4): 327-335 

18. Zhan XA, Wang M, Xu ZR, et al. Effects of fluoride on hepatic antioxidant system and transcription of Cu/Zn SOD gene in young pigs JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY 2006, 20 (2): 83-87 

19. Zhan XA, Li JX, Wang M, Xu ZR, et al. Effects of fluoride on growth and thyroid function in young pigs FLUORIDE 2006,39 (2): 95-100 

20. Zhan XA, Wang M, Xu ZR, et al. Toxic effects of fluoride on kidney function and histological structure in young pigs FLUORIDE 2006,39 (1): 22-26 

21. Feng J, Liu X, Wang YZ, Xu ZR,et al. Effects of betaine on performence, carcass characteristics and hepatic betaine-hornocysteine methyltransferase activity in finishing barrows ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 2006,19 (3): 402-405 

22. Zhan XA, Wang M, Xu ZR, et al. Evaluation of caspase-dependent apoptosis during fluoride-induced liver lesion in pigs ARCHIVES OF TOXICOLOGY 2006, 80 (2): 74-80 

23. Wang YZ, Han FF, Xu ZR Developmental gene expression of lactoferrin in duodenum and effect of weaning age on gene expression of lactoferrin in piglets ARCHIVES OF ANIMAL NUTRITION 60 (1): 1-9 FEB 2006

24. Wang, YZ; Wu, XF; Liu, GF; Cao, CP; Huang, HQ; Xu, ZR; Liu, JX Expression of porcine lactoferrin by using recombinant baculovirus in; silkworm, Bombyx mori L., and its purification and characterization. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 69 (4): 385-389 DEC 2005

25. Wang YB, Xu ZR, Xia MS The effectiveness of commercial probiotics in northern white shrimp Penaeus vannamei ponds FISHERIES SCIENCE 71 (5): 1036-1041 OCT 2005

26. Wang YB, Xu ZR, Zhou XX, et al. Bacteria attached to suspended particles in Northern White Shrimp (Penaeus vannamei L.) ponds AQUACULTURE 249 (1-4): 285-290 SEP 12 2005

27. Yan XH, Xu ZR. Production of human single-chain variable fragment (scFv) antibody specific for digoxin by ribo some display. INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 42 (6): 350-357 DEC 2005

28. Yan XH, Xu ZR, Zhang WJ, et al. Model to predict absorbed amino acid supply at the proximal duodenum in growing beef cattle.ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 18 (3): 358-363 MAR 2005

29. Tao X, Xu ZR, Wang YZ Effect of excessive dietary fluoride on nutrient digestibility and retention of iron, copper, zinc, and manganese in growing pigs BIOLOGICAL TRACE ELEMENT RESEARCH 107 (2): 141-151 NOV 2005

30. Tao X, Xu ZR, Han XY, et al. Effects of fluoride levels on lipid peroxidation and antioxidant systems of growing/finishing pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 18 (4): 552-556 APR 2005

31. Shi YH, Xu ZR, Feng JL, et al. Effects of modified montmorillonite nanocomposite on growing/finishing pigs during aflatoxicosis ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 18 (9): 1305-1309 SEP 2005

32. Shi YH, Xu ZR, Feng JL, et al. Determination of aflatoxin residue in animal tissues by high performance liquid chromatography CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 33 (6): 850-852 JUN 2005

33. Qi LF, Xu ZR, Jiang X, et al. Cytotoxic activities of chitosan nanoparticles and copper-loaded nanoparticles BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 15 (5): 1397-1399 MAR 1 2005

34. Qi LF, Xu ZR Lead sorption from aqueous solutions on chitosan nanoparticles COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 251 (1-3): 183-190 DEC 20 2004

35. Qi LF, Xu ZR, Jiang X, et al. Preparation and antibacterial activity of chitosan nanoparticles CARBOHYDRATE RESEARCH 339 (16): 2693-2700 NOV 15 2004

36. Tao X, Xu ZR, Xia MS, et al. Magnesium-aluminum mixed oxides (MAO) for alleviating fluorosis in growing-finishing pigs FLUORIDE 37 (4): 291-295 NOV 2004

37. Wei KQ, Xu ZR, Luo XG, et al. Effects of iron from an amino acid complex on the iron status of neonatal and suckling piglets ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 18 (10): 1485-1491 OCT 2005

38. Ma YL, Xu ZR, Guo T, et al. Adsorption of methylene blue on Cu(II)-exchanged montmorillonite JOURNAL OF COLLOID AND INTERFACE SCIENCE 280 (2): 283-288 DEC 15 2004

39. Guo T, Ma YL, Guo P, et al. Antibacterial effects of the Cu(II)-exchanged montmorillonite on Escherichia coli K88 and Salmonella choleraesuis VETERINARY MICROBIOLOGY 105 (2): 113-122 JAN 31 2005

40. Yu DY, Xu ZR, Yang XG Effects of lead and particulate montmorillonite on growth performance, hormone and organ weight in pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 18 (12): 1775-1779 DEC 2005 

41. Zhan XA, Li JX, Xu ZR, et al. Effects of fluoride on pancreatic digestive enzyme activities and ultrastructure in young pigs FLUORIDE 38 (3): 215-219 AUG 2005

42. Zhan XA, Xu ZR, Li JX, et al. Effects of fluorosis on lipid peroxidation and antioxidant systems in young pigs FLUORIDE 38 (2): 157-161 MAY 2005

43. Hu CH, Xu ZR, Xia MS Antibacterial effect of Cu2+-exchanged montmorillonite on Aeromonas hydrophila and discussion on its mechanism VETERINARY MICROBIOLOGY 109 (1-2): 83-88 AUG 10 2005

44. Sun JY, Jing MY, Weng XY, Fu LJ, Xu ZR, Zi NT, Wang JF Effects of dietary zinc levels on the activities of enzymes, weights of organs, and the concentrations of zinc and copper in growing rats (IF: 0.836) BIOLOGICAL TRACE ELEMENT RESEARCH 107 （2）: 153-165 NOV 2005

45. Wang Y, Tu Y, Han F, Xu Z, Wang J Developmental gene expression of lactoferrin and effect of dietary iron on gene regulation of lactoferrin in mouse mammary gland.JOURNAL OF DAIRY SCIENCE 88 （6）: 2065-2071 JUN 2005

46. Xia MS, Hu CH, Xu ZR Effects of copper bearing montmorillonite on the growth performance, intestinal microflora and morphology of weanling pigs (IF:0.895) ANIMAL FEED SCIENCE AND TECHNOLOGY 118 （3-4）: 307-317 FEB 4 2005

47. Sun JY, Liu MQ, Xu YL, Xu ZR, Pan L, Gao H Improvement of the thermostability and catalytic activity of a mesophilic family 11 xylanase by N-terminus replacement.PROTEIN EXPRESSION AND PURIFICATION 42 （1）: 122-130 JUL 2005

48. Jha RK, Xu Z R. Biotechnology and Bioethics: A bogus debate. INDOFISH 2004, VII, 1&2, 

49. Jha RK, Xu ZR, Guo BL. China’s Aquaculture Industry Marches Forward. INFOFISH International 2004; 3: 12-18.

50. Wang YZ, Xu ZR, Lin WX, Huang HQ, Wang ZQ Developmental gene expression of antimicrobial peptide PR-39 and effect of zinc oxide on gene regulation of PR-39 in piglets ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 17 （12）: 1635-1640 DEC 2004

51. Xia MS, Hu CH, Xu ZR, Ye Y, Zhou YH, Xiong L Effects of copper-bearing montmorillonite （Cu-MMT） on Escherichia coli and diarrhea on weanling pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 17（12）: 1712-1716 DEC 2004

52. Yu DY, Xu ZR, Li WF Effects of betaine on growth performance and carcass characteristics in growing pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 17 （12）: 1700-1704 DEC 2004

53. Xia MS, Hu CH, Xu ZR Effects of copper-bearing montmorillonite on growth performance, digestive enzyme activities, and intestinal microflora and morphology of male broilers POULTRY SCIENCE 83 （11）: 1868-1875 NOV 2004

54. Hu CH, Xia MS, Xu ZR, Xiong L Effects of copper-bearing montmorillonite on growth performance and digestive function of growing pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 17 （11）: 1575-1581 NOV 2004

55. Xu ZR, Han XY, Wang YZ Effects on. growth and cadmium residues from feeding cadmium-added diets with and without montmorillonite nanocomposite to growing pigs VETERINARY AND HUMAN TOXICOLOGY 46 （5）: 238-241 OCT 2004

56. Lin XL, Xu ZR, Zou XT, et al. Effects of montmorillonite nanocomposite on mercury residues in growing/finishing pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 17 （10）: 1434-1437 OCT 2004

57. Wang YZ, Xu ZR, Feng J The effect of betaine and DL-methionine on growth performance and carcass characteristics in meat ducks ANIMAL FEED SCIENCE AND TECHNOLOGY 116 （1-2）: 151-159 SEP 1 2004

58. Wang MQ, Xu ZR Effect of chromium nanoparticle on growth performance, carcass characteristics, pork quality and tissue chromium in finishing pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 17（8）: 1118-1122 AUG 2004

59. Han XY, Xu ZR, Wang YZ, et al. Effect of dietary cadmium levels on nutrient digestibility and retention of iron, copper and zinc in tissues of growing pigs ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 17 （7）: 1007-1013 JUL 2004

60. Li WF, Sun JY, Xu ZR Effects of NSP degrading enzyme on in vitro digestion of barley ASIAN AUSTRAL J ANIM 17（1）: 122-126 JAN 2004 

61. Xu ZR, Ma YL, Hu CH, et al. Effects of Cu （II）-exchanged montmorillonite on growth performance, intestinal microflora, bacterial enzyme activities and morphology of broilers ASIAN AUSTRAL J ANIM 16 （11）: 1673-1679 NOV 2003

62. Wang MQ, Xu ZR Effect of supplemental lanthanum on the growth performance of pigs ASIAN AUSTRAL J ANIM 16 （9）: 1360-1363 SEP 2003

63. Xu ZR, Hu CH, Xia MS, et al. Effects of dietary fructooligosaccharide on digestive enzyme activities, intestinal microflora and morphology of male broilers POULTRY SCI 82 （6）: 1030-1036 JUN 2003

64. He ML, Wang YZ, Xu ZR, Chen ML, Rambeck WA.Effect of dietary rare earth elements on growth performance and blood parameters of rats J ANIM PHYSIOL AN N 87 （5-6）: 229-235 JUN 2003

65. Xu ZR, Wang MQ, Mao HX, Zhan XA, Hu CH Effects of L-carnitine on growth performance, carcass composition, and metabolism of lipids in male broilers POULTRY SCI 82 （3）: 408-413 MAR 2003

66. Qian GY, Xu ZR.Effect of polysaccharide extracted from Glaciecola polaris on the protection of mouse macrophages from oxidative injury .BIORESOURCE TECHNOLOGY 98 (1): 202-206 JAN 2007

67. Huang QC, Xu ZR, Han XY, Li WF.Changes in hormones, growth factor and lipid metabolism in finishing pigs fed betaine.LIVESTOCK SCIENCE 105 (1-3): 78-85 DEC 2006

68. Du HH, Li WF, Xu ZR, Kil ZS. Effect of hyperthermia on the replication of white spot syndrome virus (WSSV) in Procambarus clarkii.DISEASES OF AQUATIC ORGANISMS 71 (2): 175-178 JUL 25 2006

69. Yan XH, Xu ZR.Ribosome-display technology: applications for directed evolution of functional proteins.DRUG DISCOVERY TODAY 11 (19-20): 911-916 OCT 2006

70. Xianghua H, Xu ZR.The use of immunoliposome for nutrient target regulation - (A review) CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION 46 (8): 629-638 DEC 2006

71. Jha RK, Xu ZR, Pandey A.Protection of Procambarus clarkii against white spot syndrome virus using recombinant subunit injection vaccine expressed in Pichia pastoris.FISHERIES SCIENCE 72 (5): 1011-1019 OCT 2006

72. Du HH, Xu ZR, Wu XF, Li WF, Dai W.Increased resistance to white spot syndrome virus in Procambarus clarkii by injection of envelope protein VP28 expressed using recombinant baculovirus.AQUACULTURE 260 (1-4): 39-43 SEP 29 2006

73. Jiang JF, Xu Z, Han XY, Wang F, Wang L.The pattern of development for gene expression of sterol regulatory element binding transcription factor 1 in pigs. CZECH JOURNAL OF ANIMAL SCIENCE 51 (6): 248-252 JUN 2006     

著作

1． 中国养猪大成. 中国农业出版社，2001，主编（篇）

2． 畜禽矿物质营养. 浙江大学出版社，1992，杭州

3． 猪的现代营养学. 浙江大学出版社，1994，杭州

4． 肉的科学与动物营养. 杭州出版社，1999，杭州

5． 动物维生素营养. 浙江大学出版社，1999，杭州

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