RESEARCH INTERESTS:

1.      Regulation of avian germline stem cell proliferation and differentiation

2.      Mechanism of sexual differentiation and embryo development

3.      Reproductive toxicology of environmental endocrine disrupters

EDUCATION:

1991.7. Ph.D. (Reproductive Biology) in College of Biological Sciences, Beijing Agricultural University and State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences

1986.7. B.S. (Animal Physiology and Biochemistry), College of Veterinary Medicine, Beijing Agricultural University

EMPLOYMENT:

2002.5.- Present, Professor, College of Animal Sciences, Zhejiang University.

2000.1.-. 2002.5. Professor, College of Biological Sciences, China Agricultural University.

1994.1.¨C1999.12. Associate professor, College of Biological Sciences, CAU

1995.4.-1997.4. Postdoctoral fellow, School of Bioagricultural Sciences, Nagoya University, Japan supported by Japan Society for Promotion of Science (JSPS).

1991.7.-1993.12. Lecturer, College of Biological Sciences, Beijing Agricultural University.

PROFESSIONAL ACTIVITIES:

1.      Standing Committee member of Chinese Association of Animal Physiology and Biochemistry

2.      Committee member of Chinese Association of Animal Anatomy, Histology and Embryology

3.      International Committee member of the International Symposium of Avian Endocrinology (ISAE) conference for 2004-2008

4.      Reviewer for General and Comparative Endocrinology, Nutrition Research, Journal of Zhejiang University (Science), Chinese Science Bulletin, Journal of Agrobiotechnology, Chinese Journal of Zoology.

TEACHING EXPERIENCE:

Graduate Courses: Animal Molecular Cell Biology, Progress in Animal Reproduction, Advances in Basic Veterinary Medicine, Laboratory of Basic Veterinary Medicine, Senior Course of Animal Physiology, Animal Cell Engineering and Laboratory, Lactation Science, Symposium of Reproductive Techniques

Undergraduate Courses: Animal Physiology, Animal Cell Biology

PUBLICATIONS:

1.      Xinyan Tang, Caiqiao Zhang. Activation of protein kinases A and C promoted proliferation of chicken primordial germ cells. Animal Reproduction Science. (in press)

2.      Dalei Zhang, Caiqiao Zhang, Jianxin Liu, Songhua Hu. Ginsenosides promote meiotic maturation of mouse oocytes in cumulus oocyte complexes involving increased expression of nitric oxide synthase. Nutrition Research. 2006 (in press)

3.      Yanmei Jin, Caiqiao Zhang, Xiaohui Lin, Weidong Zeng. Prostaglandin involvement in follicle-stimulating hormone-induced proliferation of granulosa cells from chicken prehierarchical follicles. Prostaglandins and Other Lipid Mediators. 2006, 81(1-2):45-54

4.      Hongyun Liu, Caiqiao Zhang, Weidong Zeng. Estrogenic and antioxidant effects of a phytoestrogen daidzein on ovarian germ cells in embryonic chickens. Domestic Animal Endocrinology. 2006, 31(3):258-268

5.      Hongyun Liu, Caiqiao Zhang. Ginsenosides promote proliferation of cultured ovarian germ cells involving protein kinase C-mediated system in embryonic chickens. Asian-Australasian Journal of Animal Sciences. 2006, 19(7):958-963

6.      Xinyan Tang, Caiqiao Zhang, Weidong Zeng, Yuling Mi, Hongyun Liu. Proliferating effects of flavonoids daidzein and quercetin on cultured chicken primordial germ cells through antioxidant action. Cell Biology International. 2006??30(5):445-451

7.      Xinyan Tang, Weidong Zeng, Yuling Mi, Hongyun Liu, Caiqiao Zhang. Isolation, culture and characterization of chicken primordial germ cells. Chinese Journal of Agricultural Biotechnology. (in press)

8.      Mi Y and Zhang C. Toxic and hormonal effects of polychlorinated biphenyls on cultured testicular germ cells of embryonic chickens. Toxicology Letters. 2005, 155(2):297-305

9.      Liu H, Zhang C, Tang X, Zeng W, Mi Y. Stimulating effects of androgen on proliferation of cultured ovarian germ cells through androgenic and estrogenic actions in embryonic chickens. Domestic Animal Endocrinology. 2005, 28(4):451-462

10.  Zhou C and Zhang C. Effects of antioxidant vitamins on Aroclor 1254-induced toxicity in cultured embryonic chicken hepatocytes. Toxicology in Vitro. 2005, 19(5):665-673

11.  Mi Y, Zhang C, Zeng W, Tang X. Establishment of a germ-somatic cell coculture model for toxicity assessment of environmental endocrine disrupters. Journal of Environmental Science and Health, Part A. 2005, 40(10):1917-1928

12.  Xie M, Zhang C, Zeng W, Mi Y. Effects of follicle-stimulating hormone and 17??-estradiol on germ cell development of chicken embryonic ovary in culture. Comparative Biochemistry and Physiology, Part A. 2004,139(4):521-526

13.  Xie M and Zhang C. Estrogenic and toxic effects of PCB on proliferation of chicken ovarian germ cells in culture. Reproductive Toxicology.2004, 19:79-86

14.  Mi Y, Zhang C, Xie M, Zeng W. Effects of follicle-stimulating hormone and androgen on proliferation of cultured testicular germ cells of embryonic chickens. General and Comparative Endocrinology. 2004, 138:237-246

15.  Wu H, Zhao X, Zhang C, Liu J. Establishment of mammary tissue culture: an in vitro model for bovine lactation. Journal of Animal and Feed Sciences. 2004, 13(suppl.1):575-578

16.  Zhang C and Qiao H. Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks. Journal of Zhejiang University (Science), 2004??5:193-197

17.  Zhang C, Fang C, Liu L, et al. Disrupting effects of polychlorinated biphenyls on gonadal development and reproductive functions in chickens. Journal of Environmental Science and Health. Part A??2002, A37:509-519

18.  Fang C, Zhang C, Xia G, Yang W. Damaging effect of polychlorinated biphenyls on chicken primordial germ cells. Reproduction Fertility and Development. 2002, 14:177-183

19.  Fang C, Zhang C, Qiao H, et al. Sexual difference in gonadal development of chicken embryos after treatment of polychlorinated biphenyls. Chinese Science Bulletin. 2001, 46:1900-1903

20.  Abinawanto, Zhang C, Saito N, Matsuda Y, Shimada K. Identification of sperm bearing female-specific chromosome in the sex-reversed chicken. Journal of Experimental Zoology. 1998, 280:65-72

21.  Zhang C, Shimada K, Saito N, Kansaku N.  Expressions of messenger ribonucleic acids of luteinizing hormone and follicle-stimulating hormone receptors in granulosa and theca layers of chicken preovulatory follicles. General and Comparative Endocrinology. 1997, 105:402-409